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5 years ago#1
Guest
Guest

how long does tamoxifen stay in your system after you stop taking it

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5 years ago#2
StarWish624
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Good question! Anyone out there know? I would think that it depends on your body chemistry, your dosage, age, metabolic rate (slow/fast/sluggish), and health. Ask your doctor - and then share the answer with us, please.

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5 years ago#3
lifelover
Guest

I have that same question.
I read that it can be up to 6 weeks to leave your system.
I had to stop my tamoxifen after just a year due to WEEKLy yeast infections! I have been off 2 months and still having hot flashes. I had one cycle last month. I am 48 years young so am wondering if it's menopause. I would appreciate any other insight as well.

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5 years ago#4
Isabella
Guest

1/2/2010

I was told by my oncologist that it keeps working in your body for five years. I am due to come off meds in November. It will be five years. Two years on Aridimex and then Tamoxifen. His receptionist who is also on Tamoxifen said they are now recommending you stay on it for life. Seeing as I've had no life in the last 4 years and a bit, I am finishing. I get stining in my left breast, but my breast surgeons said stinging is not a symptom of breast cancer. I trust him.

Isabella

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5 years ago#5
KR
Guest

I had been taking Tamoxifen for almost 3 and a half years as a breast cancer preventative. I had a full hysterectomy after one year on the medication. Last Spring I started having some weird symptoms (racing heart, shakiness). I was told to keep taking the meds. I decided to stop the meds this December 2009 after too many days of feeling out of it. I initially felt much better, but still have some days that feel like I did when I was on the meds. How long does it take for the Tamoxifen to leave your system? Has anyone had the same side effects that I have had? I take no other medications, except a multi-vitamin and calcium+D supplement. I know Tamoxifen is a chemotherapy type drug, but I have no idea the length of time it remains in your system. Any thoughts would be most appreciated. I have discussed this with my breast surgeon and oncologist and have not really received any substantial information from them. I am scheduled to see a cardiologist for the racing heartbeat, but my gut is telling me that the Tamoxifen still might be the cause.

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4 years ago#6
Jade
Guest

I was on Aridimx for two years and ended up with osteopenia in my spine, right hip and neck of the femur. Now I'm on Tamoxifen. I have also heard that you should stay on it for life. I agree with Isabella. There is no life on these medications. They are horrendous. I am always so tired, feel sick, bones so painful, nausea, etc. etc. I just want the old me back.


Jade

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4 years ago#7
KR
Guest

Thanks for responding. I still haven't gotten any answers from my doctors about the after effects of taking Tamoxifen. Maybe since I had the hysterectomy my body is still going through surgical menopause.I have decided to stay off the tamoxifen for now.
Take care.

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4 years ago#8
Christine
Guest

I was on tamoxifen for 3 1/2 years. I was diagnosed with breast cancer in 2006 after all the treatment 3 to 4 months after the radiation was over I suddenly had anxiety attacks (I have never had these before) I couldn't sleep and struggled to cope with every day life. Stuck with the tamoxifen until I got really bad yeast infections and headaches, oestrogen was very high 6000 I still have periods so havn't gone through the menopause. My oncologist said I could stop the tamoxifen and see how I felt, I am getting back to my old self. I do not get anxious, I can sleep!

My doctor said it could take 6 months to get the tamoxifen out of the system, I am sure on one level it does prevent the cancer coming back but it can cause no end of other problems.
Rgards Christine

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4 years ago#9
melelonj
Guest

i have been on Tamoxifen for 7 months and 2 months into it started having racing heart symptoms which led to anxiety attacks as well. I went for a full cardio work up and the cardiologist said it was likely a hormonal triggerbcz my heart was fine. I find it happens close to or during my periods. I was also put on a low dose of Lexapro which seems to maksk the symptoms since I've been back on the Tamozifen so I do feel better. I also feel better knowing I am not having heart issues.

THe frustrating thing is that the oncologist won't acknowledge the anxiety or heart racing has anything to due withthe Tamoxifen.

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4 years ago#10
StarWish624
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Did you have Chemotherapy? Chemo. can cause various heart problems. There have even been cases where people have had to have heart transplants due to the damage caused by Chemo. - although those are RARE complications:

"Heart problems and leukemia

Heart problems and leukemia are severe but rare side effects of chemotherapy. Leukemia has been linked to the use of cyclophosphamide, doxorubicin and epirubicin. Heart problems, like cardiomyopathy (enlarged, weakened heart) and congestive heart failure, have been linked to the use of doxorubicin and epirubicin, and to use of trastuzumab (for more, see Targeted Therapy). These conditions can sometimes be reversed if the drugs are stopped at the first sign of heart damage. Before you begin chemotherapy, your heart function will be measured to make sure that there are no pre-existing heart problems.

The risk of heart problems and leukemia is related to the dose of chemotherapy drugs. With the lower doses being given today, the risk of having either heart problems or leukemia is very low (less than two percent) [21].

For most people with breast cancer, the benefits of chemotherapy far outweigh these risks."
http://ww5.komen.org/BreastCancer/ LongTermSideEffectsofChemotherapy.html
---------------------------------------
http://www.chemocare.com/managing/heart_problems.asp
http://www.chemocare.com/managing/rapid_heart_beat.asp

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4 years ago#11
sad
Guest

PLEASE check this out. My sister had racing heart and had a PE. She did not survive it. I believe that the tamoxifen caused this.

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4 years ago#12
StarWish624
Champion
Blogs: 1
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"How long does Tamoxifen stay in the body after you stop taking it? There does not seem to be any definitive universal answer." This is the same answer I found time and time again. I have been doing searches on this question regularly for quite a while (hoping that there will be news), but no one says anything, except the same information. Basically, it is an individual matter. It also depends on dosage, age, and health. (But, many medications can last from 1 week to 6 months.)

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4 years ago#13
RK
Guest

KR,
I just found your post, I've been on tamoxifen for one month now and feel like I'm crawling out of my skin. I have this general anxiety, heart racing and depression that I've never had in my life. Any help about what your dr. prescribed to you would be great. Right now I just stopped taking it 4 days ago, I can't stand this.

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4 years ago#14
RK
Guest

My oncologist gave me a presctiption of 10mg of paxil to help get me thru this, I just took it about 30 minutes ago but the pharmacist said it could take UP TO TWO weeks for me to feel the effects.............argh!!

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4 years ago#15
melelonj
Guest

I am taking Lexapro for the same side affeects and it does help. Check to make sure Paxil does not inhibit the Tamoxifen. Some antidepressents are not recommended to be taken with it. My regular doctor was unaware but there is a definitive list of which are major inhibitors and which are not.
I can tell you that the anxiety has gotten better with just a baby dose of Lexapro. Hang in there...I'm a year into Tamoxifen and am finally feeling ok being on it. The first four months were an adjustment until we tried the Lexapro.

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4 years ago#16
RK
Guest

I'm not going back on Tamoxifen or any other cancer drug. The benefits don't outweigh the side effects and quality of life has to come into this. I almost went to the ER today, the anxiety and depression are overwhelming and I can't live like this. I've never felt like this in my life and it isn't worth it. I'm going back to the oncologist tomorrow, going to ask him, does he KNOW it takes Paxil 2 weeks or so to kick in? I can't make it another 2 weeks.

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4 years ago#17
RK
Guest

Oh and my oncologist said the anxiety and heart racing were completely attributed to the Tamoxifen so that's good he ackhowledges it!

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4 years ago#18
tootie
Guest

I know how you feel. I feel exactly the same

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4 years ago#19
tootie
Guest

I take Effexor for my side effects. Venafaxine is the generic name. Works quite well. I walk about 2 miles a day & that really helps for the hotflashes. I know being on Tamoxifen makes us not to have a life that we use to have. It sucks.

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4 years ago#20
tootie
Guest

My heart races or flutters once in a while. It really did when I took chemo. I hate taking the
Tamoxifen. I am so tired & no energy. I do take Venafaxine to help with the side effects of the Tamoxifen & has helped alot. I been on the Tamoxifen for 1 year now. I have not heard how long it stays in the system & how long we have to keep getting these side effects after off the Tamoxifen. Hope none of it is permament.

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4 years ago#21
tootie
Guest

ask if they can put you on Effexor or generic Vanafaxine. It did wonders for me. Exercise like walking helps the mind & the hotflashes alot.

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4 years ago#22
RK
Guest

tootie,
My oncologist prescribed me xanax today, there's only 10 but hopefully it will get me thru this hump, I can't live like this and I'm not going back on it no matter what anyone says. I will research Effexor, is it like Paxil? My heart goes out to people with these SE, I'm supposed to go back to work on Monday and there's no way if I feel like this. Best wishes to you!!

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4 years ago#23
tootie
Guest

There all antidepressents. Anything to get us thru these 5 years of hell. I get such pain in my upper back from the Tamoxifen, & I get charlie horses in my toes, calves, abdomen, & back. I feel for you to. I also thank Johnny Carson for his generous donation to build a cancer center in Norfolk, NE, upon his death of cancer. He grew up in Norfolk, NE. Prayer also helps to.

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4 years ago#24
hetti/gloucestersh ire
Guest

New years eve! 2011 tomorrow and 6 more months on tamoxifen, one part of me thinks 4yrs-6mths and only until may, the other part, can I really do another day on this drug!
Now 51yrs old and feeling like a 65yr if I could go back 4yrs:
(Q)Would I have taken Tamoxifen if I had known what was in store, how I would struggle with every side effect the drug throws at you.. including nearly a stone for every year I've taken it, having a complete personality change, lost confidence, feeling sorry for myself, how I've had a rough deal, and so would anyone who chooses to take the drugs or indeed been through BC..
(A)YES i would take it or for at least the 1st 2yrs.... your probably thinking its alright to think like that because I'm nearly at the end of the treatment.. believe me i asked that question over and over again. People ask me if I value life more having had BC? deep down its very ungratefull to think yes when really you mean no if the quality of that life is ****. But... I've made and lost 2 very good friends through BC our favourite conversation (tamoxifen) both of them struggled to the bitter end desperate to have a few more months with their young children and loved ones, the sadness and loss of people that are left hopelessly coping and trying to understand why cancer took their mum, wife, daughter... my conclusion is we all have the right to a choice to carry on the treatment or to stop...It suddenly occurred to me a few months back when i was moaning about the horrible drug tomoxifen, its the cancer what has changed your life for the worse not Tomoxifen that's saving lifes! and I'am living proof... happy new year good luck 2011 Gill James

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4 years ago#25
RK
Guest

Best wishes to you and your decision but for me the SE of the tamox are debilitating and I'm not able to cope w/everyday life, I'm definately NOT going back on it. I wonder too how much $$ these docs make prescribing us this poison. My oncologist has been "out" for the last 3 days, I ended up in the ER today with a shot of Adavan to help calm me down. I can't do this much longer.

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4 years ago#26
tootie
Guest

I heard of gals not taking the tamox. It gives us about a 10% more chance of it that the cancer don't come back. Hang in there. I agree it is poison. I hurt so bad from those side effects to.

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4 years ago#27
RK
Guest

I'll take my chances, the SE's aren'r worth it for me.

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4 years ago#28
StarWish624
Champion
Blogs: 1
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RK, sometimes the dosage can be adjusted to lessen side-effects, or make them milder. Often the side-effects can be controlled by medication, themselves. Sometimes another medication can best suit your needs. Whatever you choose, I wish you well.

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4 years ago#29
Charlotte
Bronze Member
Blogs: 1
Forum: 67
Votes: 0

Hello to everyone,Tamoxifen with all the side effects is the best,Yes leg cramps,sometimes it feel like you cannot breath one day you feeling good the next day you are sick i am also 9 month`s on tamoxifen i will take the tablet i dont want the cancer to recur,and went through treatment again,i did has cope fine with my treatment was only on panado tabs and when my white bloodcount was low on antibiotic.My Oncon.Doc.said only 5 years on Tamoxifen.Charlotte.

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4 years ago#30
angrymom
Guest

I stopped taking it 2 days ago. I have been on it for 5 months---my relationship with my nine year old is getting really bad, I am suicidal to the point that i looked up ways on the internet on what pills to take to kill me, and my personality is gone. To hell with this drug. I take 10 mg of lexapro, I even upped it to 20mg but it made no difference, so I am back to 10 mg. My onco doesn't know yet---he patronizes me half the time so I am not too keen on calling him yet. i am 49, perimenopausal, and am thinking of just having my ovaries removed, no more drugs.

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