New Support of Explanation of Breast Cancer: Smoking and Bre

New Support of Explanation of Breast Cancer

Copyright 2003, James Michael Howard, Fayetteville, Arkansas, U.S.A.

Two articles add support to my hypothesis regarding testosterone in women and breast cancer. (Find "An Explanation of Cancer and the Increase in Cancer," about the middle of www.anthropogeny.com/physiology.html .) That is, I suggest increased testosterone is involved in triggering cancer, including female breast cancer. In the first article from the January, 2004, Journal of the National
Cancer Institute, U.S.A., you will read the finding that "active smoking may play a role in breast cancer etiology." The second article demonstrates that smoking in women is connected with increased testosterone. "Current smokers had the highest testosterone concentrations with decreasing values in former and nonsmokers (p = 0.0001)." Again, I suggest this adds support to my explanation of the mechanism of cancer and I invite you read my article.

Estradiol is a one form of "female hormone" in the category "estrogen." I cannot explain why your physician was rude to you. It is my idea that estradiol increases cancer risk in the same manner as does testosterone. You will have to read the article to understand the mechanism. Therefore, not all women with breast cancer will exhibit higher testosterone levels. Again, the research reported: "Our study provides evidence that active smoking may play a role in breast cancer etiology ..." (Journal of the National Cancer Institute, Vol. 96,
No. 1, 29-37, January 7, 2004). You may choose to believe the findings or not.
One has to have an oncogene that may be triggered by this mechanism to begin breast cancer. Therefore, smoking, smoking induced increases in testosterone, or simply having high testosterone does not mean one will have breast cancer.

a working url for my explanation in detail. I invite you to go there to read my article. All supporting citations are there. However, since you responded, I will answer your statements / questions. In 2002, the Journal of the National
Cancer Institute U.S.A. said that "testosterone might be more strongly associated with [breast cancer] risk than estradiol." (citation at page) Also on my page, I suggest that my mechanism triggers "oncogenes," cancer genes. One does not have to smoke for this mechanism to trigger breast cancer oncogenes, one has to have high testosterone and low DHEA, with low DHEA being the key.
(In fact the 2004 JNCI article that caused me to repost my explanation of breast and smoking found that second hand smoke has no relationship with breast cancer, only smoking in women.) Since smoking does increase testosterone in women, the smoking is connected with breast cancer in women who have the oncogenes. Yes, increased levels of free testosterone are part of pos and, if a woman's family has breast cancer oncogenes, there is increased risk of breast cancer in pos.
Yes, not all female smokers get breast cancer; they are more likely if breast cancer genes are in their families just like in pos.

My mechanism also explains the increased cancer of old age as due to low DHEA.